Recombinant Human TNF-Related Apoptosis Inducing Ligand/Apo2L (114-281)

Size

bulk

Catalog no#

GWB-C2584C

Price

Please contact us

Group

recombinants

Old catalog number

10-663-46603

Available sizes

10ug:83,50ug:182,1000ug:1315

Source

Recombinants or rec. proteins

Category

research antibodies, ELISAs, e. Coli rec. human proteins

Store

store in freezer for long therm or fridge for short time storage

Description

This 1 is suited for programmed cell-death studies.FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Gene

Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNF╬▒, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.