>98%

0.01

0.25

5649

Canada

-20ºC

Inducer

In Stock

Synthetic

2001-95-8

White Solid

16-May-2011

C54H90N6O18

To be tested

To be tested

1111,32 g/mol

Non-hazardous

Small Molecules

Shipped Ambient

Refer to PubMed

Cancer, Apoptosis

Apoptosis Inducer

Soluble to 25 mM in DMSO and 25 mM in ethanol.

This 1 is suited for programmed cell-death studies.

1. Lars R., Jenkins A.T.A. (2007) Bioelectrochem. 70(2): 387-393. 2. Cammann K. (1985) Top Curr Chem. 128: 219-258.

(3R,6R,9S,12S,15R,18R,21S,24S,27R,30R,33S,36S)-3,6,9,15,18,21,27,30,33-Nonaisopropyl-12,24,36-trimethyl-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29, 32,35-dodecone

Chemical structure of Valinomycin (SIH-230), a Induces loss of mitochondrial membrane potential. CAS #: 2001-95-8. Molecular Formula: C54H90N6O18. Molecular Weight: 1111.32 g/mol. Chemical structure of Valinomycin, a Induces loss of mitochondrial membrane potential (SIH-230). CAS # 2001-95-8. Molecular Formula: C54H90N6O18.

Valinomycin is a dodecadepsipeptide, and a member of a group of natural neutral ionophores. It is highly selective for potassium ions within the cell membrane (1). It functions as a potassium-specific transporter and facilitates the movement of potassium ions through lipid membranes down an electrochemical potential gradient (2).

Classification: Very Toxic. May be fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible) Risk Phrases: R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed R68 - Possible risk of irreversible effects Hazard Phrases: H300-H310 Precautionary Phrases: P264-P280-P302 + P350-P310