Deprenyl, Apoptosis Inhibitor

Size

100 mg

Catalog no#

SIH-209-100MG

Price

108 EUR

Net weight (g)

0.1

Purity pourcentage

>99%

Total weight (kg)

0.25

PubChem number

26757

Country of production

Canada

Storage recommendations

-20ºC

Stock availabilitIn Stock

In Stock

Product type

Inhibitor

Origin

Synthetic

Release date

8-Apr-2011

CAS number

14611-52-0

Physical appearance

White Solid

Tested applications

To be tested

Chemical formula

C13H17N·HCl

Molecular weight

223,74 g/mol

Tested reactivity

To be tested

Warning information

Non-hazardous

Product category

Small Molecules

Shipping recommendations

Shipped Ambient

PubMed number

Refer to PubMed

Primary research fields

Cancer, Apoptosis

Description

Apoptosis Inhibitor

Soluble in

Soluble to 100 mM in water, and to 100 mM in ethanol

Other name

N-Methyl-N-[(2R)-1-phenyl-2-propanyl]-2-propyn-1-amine, Selegiline

Scientific context

Deprenyl or Selegiline is a drug used for the treatment of early stage Parkinson’s (1), depression and senile dementia (2). It is a selective irreversable inhibitor of monoamine oxidase B (MAO-b).

Bibliography

1. Lachenmayer L., and Laux G. (2004) Curr Med Chem. 11(15): 2033-2043. 2. FDA US Food and Drug Administration. Press Announcements Feb 28, 2006. www.fda.gov/newsevents/newsroom/pressannouncements/2006/ucm108607.htm

Safety information

Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R62- Possible risk of impaired fertility

Representative figure legend

Chemical structure of Deprenyl (SIH-209), a glyceraldehyde-3-phosphate dehydrogenase inhibitor. CAS #: 14611-52-0. Molecular Formula: C13H17N · HCl . Molecular Weight: 223.74 g/mol. Chemical structure of Deprenyl, a glyceraldehyde-3-phosphate dehydrogenase inhibitor (SIH-209). CAS # 14611-52-0. Molecular Formula: C13H17N · HCl .

Additional description

This 1 is suited for programmed cell-death studies.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.