Apoptosis inhibitor 5 Antibody
Size
0,1 mgCatalog no#
PA1009Price
320 EURGene Name
API5
Raised in
rabbit
Uniprot ID
Q9BZZ5
French translation
anticorps
Product form
freeze-dried
Reacts with species:
human, mouse, rat
Analyses
WB,IHC-P,IHC-F,ICC
Clone
Polyclonal antibody
Clonality
Polyclonal antibody
Target antigen
Apoptosis inhibitor 5
Gene Full Name
apoptosis inhibitor 5
Type of the antibody
IgG polyclonal antibody
Purification
Immunogen affinity purified.
Protein Name
Apoptosis inhibitor 5(API-5)
Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Apoptosis inhibitor 5(487-504aa KYSSNLGNFNYERSLQGK)(b), different from the related mouse sequence by one amino acid.
Tips
The Apoptosis inhibitor 5 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
Related articles
1. Hartz, P. A.Personal Communication.Baltimore, Md. 12/12/2005. 2. Tewari, M.; Yu, M.; Ross, B.; Dean, C.; Giordano, A.; Rubin, R. : AAC-11, a novel cDNA that inhibits apoptosis after growth factor withdrawal. Cancer Res. 57: 4063-4069, 1997.
Storage condtions
Keep the Apoptosis inhibitor 5 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
Background
Many growth factors and cytokines act as cellular survival factors by preventing programmed cell death(apoptosis). Apoptosis inhibitor 5(API5) is an antiapoptotic factor which may have a role in protein assembly. The API5 gene to chromosome 11p12 based on an alignment of the API5 sequence with the genomic sequence It is a critical determinant of E2F1-induced apoptosis, acting downstream of E2F to suppress E2F-dependent apoptosis without generally blocking E2F-dependent transcription.
Synonyms
AAC 11 antibody|AAC-11 antibody|AAC11 antibody|Antiapoptosis clone 11 protein antibody|API 5 antibody|API-5 antibody|API5 antibody|API5 like 1 antibody|API5_HUMAN antibody|API5L1 antibody|Apoptosis inhibitor 5 antibody|Cell migration inducing gene 8 protein antibody|Cell migration-inducing gene 8 protein antibody|Fibroblast growth factor 2 interacting factor 2 antibody|Fibroblast growth factor 2-interacting factor antibody|FIF antibody|MIG 8 antibody|MIG8 antibody|Migration inducing protein MIG8 antibody|Protein XAGL antibody
Description
This 1 is suited for programmed cell-death studies.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.