DcR1, ED (Decoy Receptor 1, Antagonist Decoy Receptor for TRAIL/Apo-2L, CD263, Decoy TRAIL Receptor Without Death Domain, Lymphocyte Inhibitor of TRAIL, LIT, TNF Related Apoptosis Inducing Ligand Receptor 3, TRAIL Receptor 3, TRAIL R3, TRAILR3, TRAIL-R3, Antibody

Size

50ug

Catalog no#

MBS647666

Price

536 EUR

Gene name

N/A

Gene name synonims

N/A

Other gene names

N/A

Concentration

N/A

Immunoglobulin isotype

IgG

Alternative name4

DcR1, ED

French translation

anticorps

Tissue

lymphocyte

Category

Antibodies

Clonality

Polyclonal

Other names

Dicer-1; N/A

Species reactivity

Human, Mouse, Rat

Clone

Polyclonal antibody

Host organism

Host: Rabbit; Source: Human

Purification method

Affinity Purified by immunoaffinity chromatography.

Form/Appearance

Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide.

Tested for:

ELISA (EL/EIA), Western Blot (WB), Immunofluorescence (IF)

Specificity and cross-reactivity

Recognizes human DcR1. Species Crossreactivity: mouse and rat.

Properties

If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Alternative name2

DcR1, ED (Decoy Receptor 1, Antagonist Decoy Receptor for TRAIL/Apo-2L, CD263, Decoy TRAIL Receptor Without Death Domain, Lymphocyte Inhibitor of TRAIL, LIT, TNF Related Apoptosis Inducing Ligand Receptor 3, TRAIL Receptor 3, TRAIL R3, TRAILR3, TRAIL-R3,

Alternative name3

DcR1, ED (Decoy Receptor 1, Antagonist Decoy Receptor for TRAIL/Apo-2L, CD263, Decoy TRAIL Receptor Without Death Domain, Lymphocyte Inhibitor of TRAIL, LIT, TNF Related Apoptosis Inducing Ligand Receptor 3, TRAIL Receptor 3, TRAIL R3, TRAILR3, TRAIL-R3,

Alternative name1

Anti-DcR1, ED (Decoy Receptor 1, Antagonist Decoy Receptor for TRAIL/Apo-2L, CD263, Decoy TRAIL Receptor Without Death Domain, Lymphocyte Inhibitor of TRAIL, LIT, TNF Related Apoptosis Inducing Ligand Receptor 3, TRAIL Receptor 3, TRAIL R3, TRAILR3, TRAIL-R3,

Alternative name5

Anti -DcR1, ED (Decoy Receptor 1, Antagonist Decoy Receptor for TRAIL/Apo-2L, CD263, Decoy TRAIL Receptor Without Death Domain, Lymphocyte Inhibitor of TRAIL, LIT, TNF Related Apoptosis Inducing Ligand Receptor 3, TRAIL Receptor 3, TRAIL R3, TRAILR3, TRAIL-R3,

Storage and shipping

Store at 4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, productone should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Advisory

In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

Gene

Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.

Description

productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.

Additional description

The antagonist receptor ligand binding will be in contrast with agonist activity. MBS Polyclonals produces more antagonist and receptor related products as 1.This 1 is suited for programmed cell-death studies.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.