OVA Conjugated p53 Upregulated Modulator Of Apoptosis (PUMA)
Size
500ugCatalog no#
CPB909Hu21Price
694 EURProtein length
NA
Accurate Molecular Mass(KD)
NA
Predicted Molecular Mass(KD)
NA
Purity
> 90%
Tag
No tag
Buffer Formulation
PBS, pH7.4.
Expression System
Protein Conjugation
Traits
Freeze-dried powder
Source
Protein conjugation
Organism species
Homo sapiens (Human)
Application
Immunogen; SDS-PAGE; WB
Research Area
Apoptosis;Tumor immunity;
Alternative Names
JFY1; BBC3; BCL2 Binding Component 3
Item Name
p53 Upregulated Modulator Of Apoptosis
Description
This 1 is suited for programmed cell-death studies.
Gene
Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.