OVA Conjugated p53 Upregulated Modulator Of Apoptosis (PUMA)

Size

50ug

Catalog no#

CPB909Hu21-50ug

Price

211 EUR

Notes

Research Use Only.

Additional description

This 1 is suited for programmed cell-death studies.

Description

Recombinant Human p53 Upregulated Modulator Of Apoptosis expressed in: chemical synthesis

Specifications

Host species: Homo sapiens (Human); Expression system: chemical synthesis; Expression region: Inquire; Purity: > 90%; Endotoxin level:

Additional_information

Uniprot ID: Inquire; Buffer composition: PBS, pH 7.4.; Form: Freeze-dried powder; Predicted Molecular Mass (KD): Inquire; Isoelectric Point: Inquire

Storage_and_shipping

Shipped on ice packs. Upon receipt keep at 2-8 °C for up to 1 month. For long term storage prepare working aliquots and keep frozen at -20 or -80 °C. Avoid repeated freezing and thawing.

Gene

Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.