OVA Conjugated p53 Upregulated Modulator Of Apoptosis (PUMA)

Size

10ug

Catalog no#

CPB909Hu21

Price

204 EUR

Protein length

NA

Accurate Molecular Mass(KD)

NA

Predicted Molecular Mass(KD)

NA

Purity

> 90%

Tag

No tag

Buffer Formulation

PBS, pH7.4.

Expression System

Protein Conjugation

Traits

Freeze-dried powder

Source

Protein conjugation

Organism species

Homo sapiens (Human)

Application

Immunogen; SDS-PAGE; WB

Research Area

Apoptosis;Tumor immunity;

Alternative Names

JFY1; BBC3; BCL2 Binding Component 3

Item Name

p53 Upregulated Modulator Of Apoptosis

Description

This 1 is suited for programmed cell-death studies.

Gene

Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.