Deprenyl, Apoptosis Inhibitor
Size
100 mgCatalog no#
SIH-209-100MGPrice
108 EURNet weight (g)
0.1
Purity pourcentage
>99%
Total weight (kg)
0.25
PubChem number
26757
Country of production
Canada
Storage recommendations
-20ºC
Stock availabilitIn Stock
In Stock
Product type
Inhibitor
Origin
Synthetic
Release date
8-Apr-2011
CAS number
14611-52-0
Physical appearance
White Solid
Tested applications
To be tested
Chemical formula
C13H17N·HCl
Molecular weight
223,74 g/mol
Tested reactivity
To be tested
Warning information
Non-hazardous
Product category
Small Molecules
Shipping recommendations
Shipped Ambient
PubMed number
Refer to PubMed
Primary research fields
Cancer, Apoptosis
Description
Apoptosis Inhibitor
Soluble in
Soluble to 100 mM in water, and to 100 mM in ethanol
Other name
N-Methyl-N-[(2R)-1-phenyl-2-propanyl]-2-propyn-1-amine, Selegiline
Scientific context
Deprenyl or Selegiline is a drug used for the treatment of early stage Parkinson’s (1), depression and senile dementia (2). It is a selective irreversable inhibitor of monoamine oxidase B (MAO-b).
Bibliography
1. Lachenmayer L., and Laux G. (2004) Curr Med Chem. 11(15): 2033-2043. 2. FDA US Food and Drug Administration. Press Announcements Feb 28, 2006. www.fda.gov/newsevents/newsroom/pressannouncements/2006/ucm108607.htm
Safety information
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R62- Possible risk of impaired fertility
Representative figure legend
Chemical structure of Deprenyl (SIH-209), a glyceraldehyde-3-phosphate dehydrogenase inhibitor. CAS #: 14611-52-0. Molecular Formula: C13H17N · HCl . Molecular Weight: 223.74 g/mol. Chemical structure of Deprenyl, a glyceraldehyde-3-phosphate dehydrogenase inhibitor (SIH-209). CAS # 14611-52-0. Molecular Formula: C13H17N · HCl .
Additional description
This 1 is suited for programmed cell-death studies.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.